BDBM50024894 (1R, 2S)-1,2-epoxypropyl-phosphonic acid::(2R,3S)-3-methyloxiran-2-ylphosphonate::(2R,3S)-3-methyloxiran-2-ylphosphonic acid::(3-Methyl-oxiranyl)-phosphonic acid(Na salt)::CHEMBL1757::FOSFOMYCIN::Fosfomycin (compound 1)::Fosfomycin Calcium::Fosfomycin Sodium::Monurol::phosphomycin

SMILES: C[C@@H]1O[C@@H]1P(O)(O)=O

InChI Key: InChIKey=YMDXZJFXQJVXBF-STHAYSLISA-N

Data: 5 IC50

PDB links: 12 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50024894   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MurA (E. coli) (Escherichia coli K-12 (Enterobacteria))	BDBM50024894 ((1R, 2S)-1,2-epoxypropyl-phosphonic acid | (2R,3S)...) Show SMILES C[C@@H]1O[C@@H]1P(O)(O)=O |r| Show InChI InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana, A?kerceva 7, 1000 Ljubljana, Slovenia									Bioorg Chem 55: 2-15 (2014) Article DOI: 10.1016/j.bioorg.2014.03.008 BindingDB Entry DOI: 10.7270/Q2ZG6QWR
					More data for this Ligand-Target Pair
MurA (E. coli) (Escherichia coli K-12 (Enterobacteria))	BDBM50024894 ((1R, 2S)-1,2-epoxypropyl-phosphonic acid | (2R,3S)...) Show SMILES C[C@@H]1O[C@@H]1P(O)(O)=O |r| Show InChI InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli K12 Mur A in presence of UNAG				Bioorg Med Chem Lett 16: 5605-9 (2006) Article DOI: 10.1016/j.bmcl.2006.08.021 BindingDB Entry DOI: 10.7270/Q20Z742G
					More data for this Ligand-Target Pair
MurA (E. coli) (Escherichia coli K-12 (Enterobacteria))	BDBM50024894 ((1R, 2S)-1,2-epoxypropyl-phosphonic acid | (2R,3S)...) Show SMILES C[C@@H]1O[C@@H]1P(O)(O)=O |r| Show InChI InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Escherichia coli K-12 MBP-fused C-terminal His-tagged MurA (6508 to 7768 residues) using UNAG as substrate preincubated for 10 mins fol...				Bioorg Med Chem Lett 27: 944-949 (2017) Article DOI: 10.1016/j.bmcl.2016.12.082 BindingDB Entry DOI: 10.7270/Q2ZS2ZSW
					More data for this Ligand-Target Pair
MurA (E. coli) (Escherichia coli K-12 (Enterobacteria))	BDBM50024894 ((1R, 2S)-1,2-epoxypropyl-phosphonic acid | (2R,3S)...) Show SMILES C[C@@H]1O[C@@H]1P(O)(O)=O |r| Show InChI InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Heidelberg University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli MurA expressed in Escherichia coli BL21(lamdaDE3) using UNAG and PEP as substrate incubated for 10 mins prior to PEP a...				Bioorg Med Chem 21: 795-804 (2013) Article DOI: 10.1016/j.bmc.2012.11.018 BindingDB Entry DOI: 10.7270/Q2HM59SD
					More data for this Ligand-Target Pair
MurA (P. aeruginosa) (Pseudomonas aeruginosa (G-proteobacteria))	BDBM50024894 ((1R, 2S)-1,2-epoxypropyl-phosphonic acid | (2R,3S)...) Show SMILES C[C@@H]1O[C@@H]1P(O)(O)=O |r| Show InChI InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa PAO1293 MurA in presence of UNAG				Bioorg Med Chem Lett 16: 5605-9 (2006) Article DOI: 10.1016/j.bmcl.2006.08.021 BindingDB Entry DOI: 10.7270/Q20Z742G
					More data for this Ligand-Target Pair