Found 4 hits for monomerid = 50366389 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
NH(3)-dependent NAD(+) synthetase
(Bacillus subtilis) | BDBM50366389
(GENTAMICIN)Show SMILES CN[C@H](C)[C@@H]1CC[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1 |r| Show InChI InChI=1S/C21H43N5O7/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20/h9-20,25-29H,5-8,22-24H2,1-4H3/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
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| Purchase
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PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alabama at Birmingham
Curated by ChEMBL
| Assay Description
Inhibitory activity against Bacillus subtilis NAD synthetase |
J Med Chem 46: 3371-81 (2003)
Article DOI: 10.1021/jm030003x
BindingDB Entry DOI: 10.7270/Q25T3M6Q |
More data for this
Ligand-Target Pair | |
Phospholipase A1 member A
(Rattus norvegicus) | BDBM50366389
(GENTAMICIN)Show SMILES CN[C@H](C)[C@@H]1CC[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1 |r| Show InChI InChI=1S/C21H43N5O7/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20/h9-20,25-29H,5-8,22-24H2,1-4H3/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
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PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Agricultural University of Athens
Curated by ChEMBL
| Assay Description
IC50 was measured as concentration causing 50% inhibition of lysosomal phospholipase A1 activity. |
J Med Chem 38: 4710-9 (1995)
Article DOI: 10.1021/jm00023a011
BindingDB Entry DOI: 10.7270/Q2WW7MD4 |
More data for this
Ligand-Target Pair | |
Dihydrofolate reductase (DHFR)
(Bos taurus (Cattle)) | BDBM50366389
(GENTAMICIN)Show SMILES CN[C@H](C)[C@@H]1CC[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1 |r| Show InChI InChI=1S/C21H43N5O7/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20/h9-20,25-29H,5-8,22-24H2,1-4H3/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
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PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description
Inhibition of bovine DHFR after 2 mins |
Bioorg Med Chem 18: 2849-63 (2010)
Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S |
More data for this
Ligand-Target Pair | |
Dihydrofolate reductase
(Homo sapiens (Human)) | BDBM50366389
(GENTAMICIN)Show SMILES CN[C@H](C)[C@@H]1CC[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1 |r| Show InChI InChI=1S/C21H43N5O7/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20/h9-20,25-29H,5-8,22-24H2,1-4H3/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
KEGG
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description
Inhibition of human DHFR after 2 mins |
Bioorg Med Chem 18: 2849-63 (2010)
Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S |
More data for this
Ligand-Target Pair | |
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