null

SMILES: CC(=O)C(O)=O

InChI Key: InChIKey=LCTONWCANYUPML-UHFFFAOYSA-N

PDB links: 240 PDB IDs match this monomer. 127 PDB IDs contain this monomer as substructures. 127 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 19473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monocarboxylate transporter 2 (Rattus norvegicus)	BDBM19473 (2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate) Show SMILES CC(=O)C(O)=O Show InChI InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Physiologisch-chemisches Institut der Eberhard-Karls-Universit£t T£bingen Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of lactate uptake in Xenopus laevis oocytes				Biochem J 341: 529-35 (1999) BindingDB Entry DOI: 10.7270/Q2125TQV
					More data for this Ligand-Target Pair
Solute carrier family 22 member 20 (Mus musculus)	BDBM19473 (2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate) Show SMILES CC(=O)C(O)=O Show InChI InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.71E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr				J Biol Chem 282: 23841-53 (2007) Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35
					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Mus musculus)	BDBM19473 (2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate) Show SMILES CC(=O)C(O)=O Show InChI InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.19E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr				J Biol Chem 282: 23841-53 (2007) Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35
					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member 2A1 (Homo sapiens (Human))	BDBM19473 (2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate) Show SMILES CC(=O)C(O)=O Show InChI InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	2.60E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albert Einstein College of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells				Am J Physiol Renal Physiol 282: 1097-102 (2002) Article DOI: 10.1152/ajprenal.00151.2001 BindingDB Entry DOI: 10.7270/Q21V5G7C
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase (Paramecium bursaria Chlorella virus 1)	BDBM19473 (2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate) Show SMILES CC(=O)C(O)=O Show InChI InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...				Bioorg Med Chem 27: 2405-2412 (2019) Article DOI: 10.1016/j.bmc.2019.01.018 BindingDB Entry DOI: 10.7270/Q2KK9G4R
					More data for this Ligand-Target Pair
C-terminal-binding protein 2 (Homo sapiens (Human))	BDBM19473 (2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate) Show SMILES CC(=O)C(O)=O Show InChI InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged CtBP2 (31 to 384 residues) (unknown origin) dehydrogenase activity expressed in Escherichia coli BL21-Codonplus...				Bioorg Med Chem 24: 2707-15 (2016) Article DOI: 10.1016/j.bmc.2016.04.037 BindingDB Entry DOI: 10.7270/Q28P62FX
					More data for this Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human))	BDBM19473 (2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate) Show SMILES CC(=O)C(O)=O Show InChI InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...				J Med Chem 56: 3680-8 (2013) Article DOI: 10.1021/jm400193d BindingDB Entry DOI: 10.7270/Q21V5GBQ
					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 19473

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
Acetate Operon Repressor (C-IclR) (Escherichia coli)	BDBM19473 (2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)	GoogleScholar KEGG PDB	CHEBI DrugBank KEGG MMDB PC cid PC sid PDB		7.20	8.57	-1.37	3.81	7.40	25
University of Toronto					J Biol Chem 282: 16476-91 (2007)
Acetate Operon Repressor (IclR) (Escherichia coli)	BDBM19473 (2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)	GoogleScholar KEGG PDB	CHEBI DrugBank KEGG MMDB PC cid PC sid PDB		n/a	n/a	-5.79	3.49	7.40	25
University of Toronto					J Biol Chem 282: 16476-91 (2007)