BDBM81471 CAS_91-81-6::NSC_5587::Tripelennamine

SMILES: CN(C)CCN(Cc1ccccc1)c1ccccn1

InChI Key: InChIKey=UFLGIAIHIAPJJC-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 81471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (RAT)	BDBM81471 (CAS_91-81-6 | NSC_5587 | Tripelennamine) Show SMILES CN(C)CCN(Cc1ccccc1)c1ccccn1 Show InChI InChI=1S/C16H21N3/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15/h3-11H,12-14H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 75: 6290-4 (1978) Article DOI: 10.1073/pnas.75.12.6290 BindingDB Entry DOI: 10.7270/Q2FN14P6
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM81471 (CAS_91-81-6 | NSC_5587 | Tripelennamine) Show SMILES CN(C)CCN(Cc1ccccc1)c1ccccn1 Show InChI InChI=1S/C16H21N3/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15/h3-11H,12-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Amsterdam Curated by ChEMBL					Assay Description Inhibitory activity against human Histamine H1 receptor				J Med Chem 46: 5812-24 (2003) Article DOI: 10.1021/jm030936t BindingDB Entry DOI: 10.7270/Q2GT5PF7
					More data for this Ligand-Target Pair