BDBM100289 US8501744, 5

SMILES: CC(C)C[C@H](NC(=O)c1ccc(cc1)N1CCN(C)CC1)C(=O)N1C[C@H](C)[C@H]2OCC(=O)[C@@H]12

InChI Key: InChIKey=BCYUATIIMJMQLA-CZEIZJIKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM100289 (US8501744, 5) Show SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1)N1CCN(C)CC1)C(=O)N1C[C@H](C)[C@H]2OCC(=O)[C@@H]12 |r| Show InChI InChI=1S/C25H36N4O4/c1-16(2)13-20(25(32)29-14-17(3)23-22(29)21(30)15-33-23)26-24(31)18-5-7-19(8-6-18)28-11-9-27(4)10-12-28/h5-8,16-17,20,22-23H,9-15H2,1-4H3,(H,26,31)/t17-,20-,22+,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amura Therapeutics, Limited US Patent					Assay Description In vitro cathepsin inhibition assay.				US Patent US8501744 (2013) BindingDB Entry DOI: 10.7270/Q2D7992S
					More data for this Ligand-Target Pair