BDBM100291 US8501744, 7
SMILES: C[C@H]1CN([C@H]2[C@@H]1OCC2=O)C(=O)[C@@H](NC(=O)c1ccc(cc1)N1CCN(C)CC1)C1CCCC1
InChI Key: InChIKey=KPGRBXFKZBEPEJ-UYGLSEIWSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin K (Homo sapiens (Human)) | BDBM100291 (US8501744, 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amura Therapeutics, Limited US Patent | Assay Description In vitro cathepsin inhibition assay. | US Patent US8501744 (2013) BindingDB Entry DOI: 10.7270/Q2D7992S | |||||||||||
More data for this Ligand-Target Pair |