BDBM100296 US8501744, 17

SMILES: CC(C)C[C@H](NC(=O)c1ccc(cc1)-c1csc(n1)N1CCN(C)CC1)C(=O)N1C[C@@H](C(F)F)[C@H]2OCC(=O)[C@@H]12

InChI Key: InChIKey=IUIVNOPAVOHFLU-WNXIRNOKSA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100296   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM100296 (US8501744, 17) Show SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1)-c1csc(n1)N1CCN(C)CC1)C(=O)N1C[C@@H](C(F)F)[C@H]2OCC(=O)[C@@H]12 |r| Show InChI InChI=1S/C28H35F2N5O4S/c1-16(2)12-20(27(38)35-13-19(25(29)30)24-23(35)22(36)14-39-24)31-26(37)18-6-4-17(5-7-18)21-15-40-28(32-21)34-10-8-33(3)9-11-34/h4-7,15-16,19-20,23-25H,8-14H2,1-3H3,(H,31,37)/t19-,20+,23-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amura Therapeutics, Limited US Patent					Assay Description In vitro cathepsin inhibition assay.				US Patent US8501744 (2013) BindingDB Entry DOI: 10.7270/Q2D7992S
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