null

SMILES: CCCC(Oc1ccc(cc1)-n1cc(F)cn1)c1ccc(cc1)C(=O)NCCC(O)=O

InChI Key: InChIKey=BSIHWVZFJPPICH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pro-glucagon (Homo sapiens (Human))	BDBM100790 (US8507533, 28) Show SMILES CCCC(Oc1ccc(cc1)-n1cc(F)cn1)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C23H24FN3O4/c1-2-3-21(16-4-6-17(7-5-16)23(30)25-13-12-22(28)29)31-20-10-8-19(9-11-20)27-15-18(24)14-26-27/h4-11,14-15,21H,2-3,12-13H2,1H3,(H,25,30)(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Inc. US Patent					Assay Description The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptors.				US Patent US8507533 (2013) BindingDB Entry DOI: 10.7270/Q23R0RGH
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM100790 (US8507533, 28) Show SMILES CCCC(Oc1ccc(cc1)-n1cc(F)cn1)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C23H24FN3O4/c1-2-3-21(16-4-6-17(7-5-16)23(30)25-13-12-22(28)29)31-20-10-8-19(9-11-20)27-15-18(24)14-26-27/h4-11,14-15,21H,2-3,12-13H2,1H3,(H,25,30)(H,28,29)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon-cex from human glucagon receptor by cell based assay in presence of 0.2% bovine serum albumin				Bioorg Med Chem Lett 23: 3051-8 (2013) Article DOI: 10.1016/j.bmcl.2013.03.014 BindingDB Entry DOI: 10.7270/Q27M099R
					More data for this Ligand-Target Pair