BDBM101240 US8524722, 123
SMILES: CC(C)C(C)C\C=C\C(=O)N1CCc2c(C1)sc1ncnc(Nc3cc(O)cc(Cl)c3)c21
InChI Key: InChIKey=FHNHKAFWHQJIDM-GQCTYLIASA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM101240 (US8524722, 123) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description EGFR inhibitory activity of compounds of the present invention is quantified employing the EGFR HTRF assay. | US Patent US8524722 (2013) BindingDB Entry DOI: 10.7270/Q2B856RQ | |||||||||||
More data for this Ligand-Target Pair |