new BindingDB logo
myBDB logout

BDBM101295 US8524717, 50

SMILES: CN1CCN(CC1)C(=O)CN[C@H]1C[C@@H]1c1ccc(cc1)-c1ccccc1C(F)(F)F

InChI Key: InChIKey=DULMWURFXBPWNL-CTNGQTDRSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 101295   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM101295
PNG
(US8524717, 50)
Show SMILES CN1CCN(CC1)C(=O)CN[C@H]1C[C@@H]1c1ccc(cc1)-c1ccccc1C(F)(F)F |r|
Show InChI InChI=1S/C23H26F3N3O/c1-28-10-12-29(13-11-28)22(30)15-27-21-14-19(21)17-8-6-16(7-9-17)18-4-2-3-5-20(18)23(24,25)26/h2-9,19,21,27H,10-15H2,1H3/t19-,21+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
160n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Biological assay using monoamine oxidase or LSD1.


US Patent US8524717 (2013)


BindingDB Entry DOI: 10.7270/Q26H4G1D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM101295
PNG
(US8524717, 50)
Show SMILES CN1CCN(CC1)C(=O)CN[C@H]1C[C@@H]1c1ccc(cc1)-c1ccccc1C(F)(F)F |r|
Show InChI InChI=1S/C23H26F3N3O/c1-28-10-12-29(13-11-28)22(30)15-27-21-14-19(21)17-8-6-16(7-9-17)18-4-2-3-5-20(18)23(24,25)26/h2-9,19,21,27H,10-15H2,1H3/t19-,21+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.50E+4n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Biological assay using monoamine oxidase or LSD1.


US Patent US8524717 (2013)


BindingDB Entry DOI: 10.7270/Q26H4G1D
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM101295
PNG
(US8524717, 50)
Show SMILES CN1CCN(CC1)C(=O)CN[C@H]1C[C@@H]1c1ccc(cc1)-c1ccccc1C(F)(F)F |r|
Show InChI InChI=1S/C23H26F3N3O/c1-28-10-12-29(13-11-28)22(30)15-27-21-14-19(21)17-8-6-16(7-9-17)18-4-2-3-5-20(18)23(24,25)26/h2-9,19,21,27H,10-15H2,1H3/t19-,21+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
>4.00E+4n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Biological assay using monoamine oxidase or LSD1.


US Patent US8524717 (2013)


BindingDB Entry DOI: 10.7270/Q26H4G1D
More data for this
Ligand-Target Pair