BDBM101302 CHEMBL3108900::US8524717, 57
SMILES: CN1CCN(CC1)C(=O)CN[C@H]1C[C@@H]1c1ccc(cc1)-c1cc(F)ccc1C(F)(F)F
InChI Key: InChIKey=ACGHLMNRRAVGJC-CTNGQTDRSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM101302 (CHEMBL3108900 | US8524717, 57) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of South Carolina Curated by ChEMBL | Assay Description Inhibition of human recombinant LSD1 using di-methylated H3-K4 peptide as substrate assessed as release of H2O2 preincubated for 15 mins followed by ... | ACS Med Chem Lett 5: 29-33 (2014) Article DOI: 10.1021/ml4002997 BindingDB Entry DOI: 10.7270/Q2HT2QS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM101302 (CHEMBL3108900 | US8524717, 57) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oryzon Genomics, S.A. US Patent | Assay Description Biological assay using monoamine oxidase or LSD1. | US Patent US8524717 (2013) BindingDB Entry DOI: 10.7270/Q26H4G1D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM101302 (CHEMBL3108900 | US8524717, 57) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 1.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oryzon Genomics, S.A. US Patent | Assay Description Biological assay using monoamine oxidase or LSD1. | US Patent US8524717 (2013) BindingDB Entry DOI: 10.7270/Q26H4G1D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM101302 (CHEMBL3108900 | US8524717, 57) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oryzon Genomics, S.A. US Patent | Assay Description Biological assay using monoamine oxidase or LSD1. | US Patent US8524717 (2013) BindingDB Entry DOI: 10.7270/Q26H4G1D | |||||||||||
More data for this Ligand-Target Pair |