BDBM101485 US8524710, 62::US8530652, 12::US8530652, 56

SMILES: CC1(C)N(Cc2c(Nc3nc(Cl)nc4ccccc34)[nH]nc12)C(=O)NC1CC1c1ccccc1

InChI Key: InChIKey=OJCCWUWPMWSEBG-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101485   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM101485 (US8524710, 62 | US8530652, 12 | US8530652, 56) Show SMILES CC1(C)N(Cc2c(Nc3nc(Cl)nc4ccccc34)[nH]nc12)C(=O)NC1CC1c1ccccc1 Show InChI InChI=1S/C25H24ClN7O/c1-25(2)20-17(13-33(25)24(34)28-19-12-16(19)14-8-4-3-5-9-14)22(32-31-20)29-21-15-10-6-7-11-18(15)27-23(26)30-21/h3-11,16,19H,12-13H2,1-2H3,(H,28,34)(H2,27,29,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	38	n/a	n/a	n/a	78	n/a	n/a	n/a	n/a
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent					Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...				US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4
					More data for this Ligand-Target Pair