BDBM101518 US8524699, 46::US8530652, 45::US8530652, 90

SMILES: CC1(C)N(Cc2c(Nc3nc(nc4ccsc34)C(F)(F)F)[nH]nc12)C(=O)N[C@@H]1C[C@H]1c1ccccc1

InChI Key: InChIKey=KVRSZGOQCJDJIC-XJKSGUPXSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM101518 (US8524699, 46 | US8530652, 45 | US8530652, 90) Show SMILES CC1(C)N(Cc2c(Nc3nc(nc4ccsc34)C(F)(F)F)[nH]nc12)C(=O)N[C@@H]1C[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C24H22F3N7OS/c1-23(2)18-14(11-34(23)22(35)29-16-10-13(16)12-6-4-3-5-7-12)19(33-32-18)30-20-17-15(8-9-36-17)28-21(31-20)24(25,26)27/h3-9,13,16H,10-11H2,1-2H3,(H,29,35)(H2,28,30,31,32,33)/t13-,16+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	25	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent					Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...				US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4
					More data for this Ligand-Target Pair