BDBM101547 US8530494, 212::US8530652, 126::US8530652, 74

SMILES: CN(C)C[C@@H](OC(=O)N1Cc2c(Nc3nc(nc4ccccc34)C#N)[nH]nc2C1(C)C)c1ccccc1

InChI Key: InChIKey=GIMPURVXYMDEBA-OAQYLSRUSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101547   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM101547 (US8530494, 212 | US8530652, 126 | US8530652, 74) Show SMILES CN(C)C[C@@H](OC(=O)N1Cc2c(Nc3nc(nc4ccccc34)C#N)[nH]nc2C1(C)C)c1ccccc1 |r| Show InChI InChI=1S/C27H28N8O2/c1-27(2)23-19(15-35(27)26(36)37-21(16-34(3)4)17-10-6-5-7-11-17)25(33-32-23)31-24-18-12-8-9-13-20(18)29-22(14-28)30-24/h5-13,21H,15-16H2,1-4H3,(H2,29,30,31,32,33)/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.60	n/a	n/a	n/a	<3.90	n/a	n/a	n/a	n/a
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent					Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...				US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4
					More data for this Ligand-Target Pair