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BDBM101548 US8530494, 108::US8530652, 127::US8530652, 75

SMILES: CN(C)C[C@@H](OC(=O)N1Cc2c(Nc3ncnc4sccc34)[nH]nc2C1(C)C)c1ccccc1

InChI Key: InChIKey=XXKGDIQXCWLQED-GOSISDBHSA-N

Data: 1 KI  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101548   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PAK 4


(Homo sapiens (Human))		BDBM101548
PNG
(US8530494, 108 | US8530652, 127 | US8530652, 75)
Show SMILES CN(C)C[C@@H](OC(=O)N1Cc2c(Nc3ncnc4sccc34)[nH]nc2C1(C)C)c1ccccc1 |r|
Show InChI InChI=1S/C24H27N7O2S/c1-24(2)19-17(21(29-28-19)27-20-16-10-11-34-22(16)26-14-25-20)12-31(24)23(32)33-18(13-30(3)4)15-8-6-5-7-9-15/h5-11,14,18H,12-13H2,1-4H3,(H2,25,26,27,28,29)/t18-/m1/s1
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Similars
US Patent
 5.20n/an/an/a<3.90n/an/an/an/a



Agouron Pharmaceuticals, Inc.; Pfizer Inc.

US Patent


Assay Description
The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...

US Patent US8530652 (2013)


BindingDB Entry DOI: 10.7270/Q2F18XC4
More data for this
Ligand-Target Pair