BDBM10176 (2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-6-hydroxyhexyl]-2-[(4-hydroxyphenyl)formamido]-3,3-diphenylpropanamide::lysine sulfonamide analogue 37

SMILES: CC(C)CN(C(CO)CCCCNC(=O)[C@@H](NC(=O)c1ccc(O)cc1)C(c1ccccc1)c1ccccc1)S(=O)(=O)c1ccc(N)cc1

InChI Key: InChIKey=YAOSIGBNGZRGFR-UYQMNGSLSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10176   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Protease (Human immunodeficiency virus type 1)	BDBM10176 ((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...) Show SMILES CC(C)CN(C(CO)CCCCNC(=O)[C@@H](NC(=O)c1ccc(O)cc1)C(c1ccccc1)c1ccccc1)S(=O)(=O)c1ccc(N)cc1 |r| Show InChI InChI=1S/C38H46N4O6S/c1-27(2)25-42(49(47,48)34-22-18-31(39)19-23-34)32(26-43)15-9-10-24-40-38(46)36(41-37(45)30-16-20-33(44)21-17-30)35(28-11-5-3-6-12-28)29-13-7-4-8-14-29/h3-8,11-14,16-23,27,32,35-36,43-44H,9-10,15,24-26,39H2,1-2H3,(H,40,46)(H,41,45)/t32?,36-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.470	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
Ambrilia Biopharma Inc.					Assay Description HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...				Bioorg Med Chem Lett 16: 3459-62 (2006) Article DOI: 10.1016/j.bmcl.2006.04.011 BindingDB Entry DOI: 10.7270/Q2RB72T4
					More data for this Ligand-Target Pair