BDBM102424 FIDAS-3::Fluorinated N,N-Dialkylaminostilbenes 3

SMILES: CN(C)c1ccc(\C=C\c2c(F)cccc2F)cc1

InChI Key: InChIKey=YBJDCOLXJYDHOM-DHZHZOJOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM102424 (FIDAS-3 | Fluorinated N,N-Dialkylaminostilbenes 3) Show SMILES CN(C)c1ccc(\C=C\c2c(F)cccc2F)cc1 Show InChI InChI=1S/C16H15F2N/c1-19(2)13-9-6-12(7-10-13)8-11-14-15(17)4-3-5-16(14)18/h3-11H,1-2H3/b11-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of human ERG over-expressed in HEK293 cell membrane by [3H]dofetilide binding assay				J Med Chem 57: 6083-91 (2014) Article DOI: 10.1021/jm5004864 BindingDB Entry DOI: 10.7270/Q22R3T8G
					More data for this Ligand-Target Pair
MAT2A (Escherichia coli)	BDBM102424 (FIDAS-3 | Fluorinated N,N-Dialkylaminostilbenes 3) Show SMILES CN(C)c1ccc(\C=C\c2c(F)cccc2F)cc1 Show InChI InChI=1S/C16H15F2N/c1-19(2)13-9-6-12(7-10-13)8-11-14-15(17)4-3-5-16(14)18/h3-11H,1-2H3/b11-8+	PDB GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky					Assay Description MAT2A was incubated with FIDAS agents at RT for 20 min andthen mixed with L-methionine and ATP in 0.5 mL of reaction buffer.Cold deionized water (2 m...				ACS Chem Biol 8: 796-803 (2013) Article DOI: 10.1021/cb3005353 BindingDB Entry DOI: 10.7270/Q2W37TZV
					More data for this Ligand-Target Pair