BDBM102989 US8546451, VII

SMILES: Oc1ccc(cc1)N(C(=O)c1ccc(O)c(F)c1)c1ccc(O)cc1

InChI Key: InChIKey=VLJZTJRWPPMWCP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM102989 (US8546451, VII) Show SMILES Oc1ccc(cc1)N(C(=O)c1ccc(O)c(F)c1)c1ccc(O)cc1 Show InChI InChI=1S/C19H14FNO4/c20-17-11-12(1-10-18(17)24)19(25)21(13-2-6-15(22)7-3-13)14-4-8-16(23)9-5-14/h1-11,22-24H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.06	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GTx, Inc. US Patent					Assay Description The ER binding affinity of the compounds was determined using an in vitro competitive radioligand binding assay was [2,4,6,7-3H(N)]-Estradiol ([3H]E2...				US Patent US8546451 (2013) BindingDB Entry DOI: 10.7270/Q2XW4HFH
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM102989 (US8546451, VII) Show SMILES Oc1ccc(cc1)N(C(=O)c1ccc(O)c(F)c1)c1ccc(O)cc1 Show InChI InChI=1S/C19H14FNO4/c20-17-11-12(1-10-18(17)24)19(25)21(13-2-6-15(22)7-3-13)14-4-8-16(23)9-5-14/h1-11,22-24H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	76.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GTx, Inc. US Patent					Assay Description The ER binding affinity of the compounds was determined using an in vitro competitive radioligand binding assay was [2,4,6,7-3H(N)]-Estradiol ([3H]E2...				US Patent US8546451 (2013) BindingDB Entry DOI: 10.7270/Q2XW4HFH
					More data for this Ligand-Target Pair