BDBM103258 US8546389, 112

SMILES: CNC(=O)c1n(nc2cc(N(CCN3CCOCC3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Oc2ccc(F)cc2)cc1

InChI Key: InChIKey=SHTFLWGXAKRVFU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (NS5B) (Hepatitis C virus genotype 3a (isolate NZL1) (HCV))	BDBM103258 (US8546389, 112) Show SMILES CNC(=O)c1n(nc2cc(N(CCN3CCOCC3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C31H34FN5O5S/c1-33-31(38)30-27-19-26(21-3-4-21)29(36(43(2,39)40)14-13-35-15-17-41-18-16-35)20-28(27)34-37(30)23-7-11-25(12-8-23)42-24-9-5-22(32)6-10-24/h5-12,19-21H,3-4,13-18H2,1-2H3,(H,33,38)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair
Non-structural protein 5B (NS5B) (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM103258 (US8546389, 112) Show SMILES CNC(=O)c1n(nc2cc(N(CCN3CCOCC3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C31H34FN5O5S/c1-33-31(38)30-27-19-26(21-3-4-21)29(36(43(2,39)40)14-13-35-15-17-41-18-16-35)20-28(27)34-37(30)23-7-11-25(12-8-23)42-24-9-5-22(32)6-10-24/h5-12,19-21H,3-4,13-18H2,1-2H3,(H,33,38)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair