BDBM103260 US8546389, 119

SMILES: CNC(=O)c1n(nc2cc(N(CCCNC(C)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Nc2ccc(F)cc2)cc1

InChI Key: InChIKey=GDFKILQECCBXRF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (NS5B) (Hepatitis C virus genotype 3a (isolate NZL1) (HCV))	BDBM103260 (US8546389, 119) Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(C)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C30H33FN6O4S/c1-19(38)33-15-4-16-36(42(3,40)41)28-18-27-26(17-25(28)20-5-6-20)29(30(39)32-2)37(35-27)24-13-11-23(12-14-24)34-22-9-7-21(31)8-10-22/h7-14,17-18,20,34H,4-6,15-16H2,1-3H3,(H,32,39)(H,33,38)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair
Non-structural protein 5B (NS5B) (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM103260 (US8546389, 119) Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(C)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C30H33FN6O4S/c1-19(38)33-15-4-16-36(42(3,40)41)28-18-27-26(17-25(28)20-5-6-20)29(30(39)32-2)37(35-27)24-13-11-23(12-14-24)34-22-9-7-21(31)8-10-22/h7-14,17-18,20,34H,4-6,15-16H2,1-3H3,(H,32,39)(H,33,38)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair