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SMILES: CNC(=O)c1n(nc2cc(N(CCCNC(=O)c3cccnc3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1

InChI Key: InChIKey=DPLBSVCORAUCFV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 3a (isolate NZL1) (HCV))	BDBM103276 (US8546389, 191) Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(=O)c3cccnc3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 Show InChI InChI=1S/C28H29BrN6O4S/c1-30-28(37)26-23-15-22(18-6-7-18)25(16-24(23)33-35(26)21-10-8-20(29)9-11-21)34(40(2,38)39)14-4-13-32-27(36)19-5-3-12-31-17-19/h3,5,8-12,15-18H,4,6-7,13-14H2,1-2H3,(H,30,37)(H,32,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM103276 (US8546389, 191) Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(=O)c3cccnc3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 Show InChI InChI=1S/C28H29BrN6O4S/c1-30-28(37)26-23-15-22(18-6-7-18)25(16-24(23)33-35(26)21-10-8-20(29)9-11-21)34(40(2,38)39)14-4-13-32-27(36)19-5-3-12-31-17-19/h3,5,8-12,15-18H,4,6-7,13-14H2,1-2H3,(H,30,37)(H,32,36)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair