BDBM103279 US8546389, 234

SMILES: CNC(=O)c1n(nc2cc(N(C)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1

InChI Key: InChIKey=WNHZRNGIHSKSCU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (NS5B) (Hepatitis C virus genotype 3a (isolate NZL1) (HCV))	BDBM103279 (US8546389, 234) Show SMILES CNC(=O)c1n(nc2cc(N(C)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 Show InChI InChI=1S/C20H21BrN4O3S/c1-22-20(26)19-16-10-15(12-4-5-12)18(24(2)29(3,27)28)11-17(16)23-25(19)14-8-6-13(21)7-9-14/h6-12H,4-5H2,1-3H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair
Non-structural protein 5B (NS5B) (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM103279 (US8546389, 234) Show SMILES CNC(=O)c1n(nc2cc(N(C)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 Show InChI InChI=1S/C20H21BrN4O3S/c1-22-20(26)19-16-10-15(12-4-5-12)18(24(2)29(3,27)28)11-17(16)23-25(19)14-8-6-13(21)7-9-14/h6-12H,4-5H2,1-3H3,(H,22,26)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair