BDBM103279 US8546389, 234
SMILES: CNC(=O)c1n(nc2cc(N(C)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1
InChI Key: InChIKey=WNHZRNGIHSKSCU-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RNA-directed RNA polymerase (NS5B) (Hepatitis C virus genotype 3a (isolate NZL1) (HCV)) | BDBM103279 (US8546389, 234) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Biota Scientific Management Pty Ltd. US Patent | Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe... | US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-structural protein 5B (NS5B) (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM103279 (US8546389, 234) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Biota Scientific Management Pty Ltd. US Patent | Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe... | US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK | |||||||||||
More data for this Ligand-Target Pair |