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SMILES: CNC(=O)c1n(nc2cc(N(CCC3COC(C)(C)OC3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1

InChI Key: InChIKey=YWQNEOKUXRIHPA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 3a (isolate NZL1) (HCV))	BDBM103287 (US8546389, 95) Show SMILES CNC(=O)c1n(nc2cc(N(CCC3COC(C)(C)OC3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 Show InChI InChI=1S/C27H33BrN4O5S/c1-27(2)36-15-17(16-37-27)11-12-31(38(4,34)35)24-14-23-22(13-21(24)18-5-6-18)25(26(33)29-3)32(30-23)20-9-7-19(28)8-10-20/h7-10,13-14,17-18H,5-6,11-12,15-16H2,1-4H3,(H,29,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM103287 (US8546389, 95) Show SMILES CNC(=O)c1n(nc2cc(N(CCC3COC(C)(C)OC3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 Show InChI InChI=1S/C27H33BrN4O5S/c1-27(2)36-15-17(16-37-27)11-12-31(38(4,34)35)24-14-23-22(13-21(24)18-5-6-18)25(26(33)29-3)32(30-23)20-9-7-19(28)8-10-20/h7-10,13-14,17-18H,5-6,11-12,15-16H2,1-4H3,(H,29,33)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair