BDBM103300 US8546404, 571
SMILES: C[C@@H]1CN(CCN1C(=O)CN1CCC(C1)(C#C)C(=O)Nc1ccc2[nH]nc(-c3ccc(F)cc3)c2c1)c1ccc(cn1)-c1ncccn1
InChI Key: InChIKey=WYYCGJHDDHWKSD-LHTANEHXSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM103300 (US8546404, 571) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 19.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme US Patent | Assay Description Activated ERK2 activity was determined in the IMAP assay format. | US Patent US8546404 (2013) BindingDB Entry DOI: 10.7270/Q2959G61 | |||||||||||
More data for this Ligand-Target Pair |