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SMILES: C[C@@H](N(C\C=C\c1ccc2C[C@@]3(Cc2c1)N(C)C(=O)NC3=O)C(=O)C(C)(C)C)c1cc(F)cc(F)c1

InChI Key: InChIKey=VSGHIDXTENKDGR-AVTHMAOQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103496   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))		BDBM103496
PNG
(US8552023, 8)
Show SMILES C[C@@H](N(C\C=C\c1ccc2C[C@@]3(Cc2c1)N(C)C(=O)NC3=O)C(=O)C(C)(C)C)c1cc(F)cc(F)c1 |r|
Show InChI InChI=1S/C28H31F2N3O3/c1-17(20-12-22(29)14-23(30)13-20)33(25(35)27(2,3)4)10-6-7-18-8-9-19-15-28(16-21(19)11-18)24(34)31-26(36)32(28)5/h6-9,11-14,17H,10,15-16H2,1-5H3,(H,31,34,36)/b7-6+/t17-,28+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 0.430n/an/an/an/an/an/a7.4n/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.

US Patent US8552023 (2013)


BindingDB Entry DOI: 10.7270/Q2VX0F4V
More data for this
Ligand-Target Pair