BDBM103517 US8546370, 130

SMILES: CC(C)Cn1cc(cn1)-c1cc2cc[nH]c(=O)c2c(Nc2ccc(cc2)C2CCN(CC2)C(C)=O)n1

InChI Key: InChIKey=JQHIOBMPLJEDMM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM103517 (US8546370, 130) Show SMILES CC(C)Cn1cc(cn1)-c1cc2cc[nH]c(=O)c2c(Nc2ccc(cc2)C2CCN(CC2)C(C)=O)n1 Show InChI InChI=1S/C28H32N6O2/c1-18(2)16-34-17-23(15-30-34)25-14-22-8-11-29-28(36)26(22)27(32-25)31-24-6-4-20(5-7-24)21-9-12-33(13-10-21)19(3)35/h4-8,11,14-15,17-18,21H,9-10,12-13,16H2,1-3H3,(H,29,36)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
IRM LLC US Patent					Assay Description Homogenous time-resolved fluorescence assay using Syk enzyme.				US Patent US8546370 (2013) BindingDB Entry DOI: 10.7270/Q2GQ6WDM
					More data for this Ligand-Target Pair