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SMILES: COc1cncc(n1)-c1cc2cc[nH]c(=O)c2c(Nc2ccc(C3CCOCC3)c(C)c2)n1

InChI Key: InChIKey=PSJBOAXOFQUTFP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103530   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase ZAP-70


(Homo sapiens (Human))		BDBM103530
PNG
(US8546370, 643)
Show SMILES COc1cncc(n1)-c1cc2cc[nH]c(=O)c2c(Nc2ccc(C3CCOCC3)c(C)c2)n1
Show InChI InChI=1S/C25H25N5O3/c1-15-11-18(3-4-19(15)16-6-9-33-10-7-16)28-24-23-17(5-8-27-25(23)31)12-20(30-24)21-13-26-14-22(29-21)32-2/h3-5,8,11-14,16H,6-7,9-10H2,1-2H3,(H,27,31)(H,28,30)
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US Patent
n/an/a 31n/an/an/an/an/an/a



IRM LLC

US Patent


Assay Description
Homogenous time-resolved fluorescence assay using Syk enzyme.

US Patent US8546370 (2013)


BindingDB Entry DOI: 10.7270/Q2GQ6WDM
More data for this
Ligand-Target Pair