BDBM103942 US10399973, Example 17::US8569338, 24::US9035066, 17::US9493457, 17::US9890160, Example 17
SMILES: CC(C)C1N(CCc2nc[nH]c12)C(=O)OCC1CCOC1
InChI Key: InChIKey=YYEWOALXGQHVJR-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular adhesion protein 1 (VAP-1) (Homo sapiens (Human)) | BDBM103942 (US10399973, Example 17 | US8569338, 24 | US9035066...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | 25 |
Proximagen Ltd. US Patent | Assay Description All assays were performed in room temperature with purified recombinantly expressed human SSAO. The enzyme activity was measured with benzylamine as... | US Patent US8569338 (2013) BindingDB Entry DOI: 10.7270/Q2P849J0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular adhesion protein 1 (VAP-1) (Homo sapiens (Human)) | BDBM103942 (US10399973, Example 17 | US8569338, 24 | US9035066...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 91 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Proximagen Limited US Patent | Assay Description Briefly, test compounds were dissolved in dimethyl sulfoxide (DMSO) to a concentration of 10 mM. Dose-response measurements were assayed by either cr... | US Patent US9035066 (2015) BindingDB Entry DOI: 10.7270/Q2G15ZKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular adhesion protein 1 (VAP-1) (Homo sapiens (Human)) | BDBM103942 (US10399973, Example 17 | US8569338, 24 | US9035066...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
BENEVOLENTAI CAMBRIDGE LIMITED US Patent | Assay Description All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman... | US Patent US10399973 (2019) BindingDB Entry DOI: 10.7270/Q2PR7ZCK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular adhesion protein 1 (VAP-1) (Homo sapiens (Human)) | BDBM103942 (US10399973, Example 17 | US8569338, 24 | US9035066...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Astex | Assay Description Briefly, test compounds were dissolved in dimethyl sulfoxide (DMSO) to a concentration of 10 mM. Dose-response measurements were assayed by either cr... | J Med Chem 51: 4986-99 (2008) BindingDB Entry DOI: 10.7270/Q2348NQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular adhesion protein 1 (VAP-1) (Homo sapiens (Human)) | BDBM103942 (US10399973, Example 17 | US8569338, 24 | US9035066...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 91 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Proximagen Limited US Patent | Assay Description Briefly, test compounds were dissolved in dimethyl sulfoxide (DMSO) to a concentration of 10 mM. Dose-response measurements were assayed by either cr... | US Patent US9493457 (2016) BindingDB Entry DOI: 10.7270/Q2MK6BSS | |||||||||||
More data for this Ligand-Target Pair |