BDBM104066 HS43
SMILES: OCCSc1nc2n(ncc2c(=O)[nH]1)-c1cccc(Cl)c1
InChI Key: InChIKey=JFVHRGLFYNOUDO-UHFFFAOYSA-N
Data: 6 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Death-associated protein kinase 1 (Homo sapiens (Human)) | BDBM104066 (HS43) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a |
Duke University Medical Center | Assay Description HS38 was evaluated using a P-33 ATP filter-binding assay by the International Centre for Kinase Profiling (University of Dundee) against 124 purified... | ACS Chem Biol 8: 2715-23 (2013) Article DOI: 10.1021/cb400407c BindingDB Entry DOI: 10.7270/Q24B2ZXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Death-associated protein kinase 1 (Homo sapiens (Human)) | BDBM104066 (HS43) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a |
Duke University Medical Center | Assay Description HS38 was evaluated using a P-33 ATP filter-binding assay by the International Centre for Kinase Profiling (University of Dundee) against 124 purified... | ACS Chem Biol 8: 2715-23 (2013) Article DOI: 10.1021/cb400407c BindingDB Entry DOI: 10.7270/Q24B2ZXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human)) | BDBM104066 (HS43) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a |
Duke University Medical Center | Assay Description HS38 was evaluated using a P-33 ATP filter-binding assay by the International Centre for Kinase Profiling (University of Dundee) against 124 purified... | ACS Chem Biol 8: 2715-23 (2013) Article DOI: 10.1021/cb400407c BindingDB Entry DOI: 10.7270/Q24B2ZXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM104066 (HS43) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a |
Duke University Medical Center | Assay Description HS38 was evaluated using a P-33 ATP filter-binding assay by the International Centre for Kinase Profiling (University of Dundee) against 124 purified... | ACS Chem Biol 8: 2715-23 (2013) Article DOI: 10.1021/cb400407c BindingDB Entry DOI: 10.7270/Q24B2ZXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human)) | BDBM104066 (HS43) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a |
Duke University Medical Center | Assay Description HS38 was evaluated using a P-33 ATP filter-binding assay by the International Centre for Kinase Profiling (University of Dundee) against 124 purified... | ACS Chem Biol 8: 2715-23 (2013) Article DOI: 10.1021/cb400407c BindingDB Entry DOI: 10.7270/Q24B2ZXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Death-associated protein kinase 1 (Homo sapiens (Human)) | BDBM104066 (HS43) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a |
Duke University Medical Center | Assay Description HS38 was evaluated using a P-33 ATP filter-binding assay by the International Centre for Kinase Profiling (University of Dundee) against 124 purified... | ACS Chem Biol 8: 2715-23 (2013) Article DOI: 10.1021/cb400407c BindingDB Entry DOI: 10.7270/Q24B2ZXR | |||||||||||
More data for this Ligand-Target Pair |