BDBM104165 US8575145, 42

SMILES: N[C@H]1CCC(CC1)Oc1cccc2ccc(nc12)-c1nnc2ccccn12

InChI Key: InChIKey=QFYWUMPWXIJTRE-JGIIQEAISA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 104165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM104165 (US8575145, 42) Show SMILES N[C@H]1CCC(CC1)Oc1cccc2ccc(nc12)-c1nnc2ccccn12 |r,wU:1.0,(7.59,3.85,;6.26,3.08,;6.26,1.54,;4.93,.77,;3.6,1.54,;3.6,3.08,;4.93,3.85,;2.27,.77,;2.27,-.77,;3.61,-1.54,;3.61,-3.08,;2.27,-3.85,;.94,-3.08,;-.4,-3.85,;-1.73,-3.08,;-1.73,-1.54,;-.4,-.77,;.94,-1.54,;-3.06,-.77,;-3.06,.77,;-4.53,1.25,;-5.43,0,;-6.96,-.16,;-7.59,-1.56,;-6.69,-2.81,;-5.15,-2.65,;-4.53,-1.24,)| Show InChI InChI=1S/C21H21N5O/c22-15-8-10-16(11-9-15)27-18-5-3-4-14-7-12-17(23-20(14)18)21-25-24-19-6-1-2-13-26(19)21/h1-7,12-13,15-16H,8-11,22H2/t15-,16?	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM104165 (US8575145, 42) Show SMILES N[C@H]1CCC(CC1)Oc1cccc2ccc(nc12)-c1nnc2ccccn12 |r,wU:1.0,(7.59,3.85,;6.26,3.08,;6.26,1.54,;4.93,.77,;3.6,1.54,;3.6,3.08,;4.93,3.85,;2.27,.77,;2.27,-.77,;3.61,-1.54,;3.61,-3.08,;2.27,-3.85,;.94,-3.08,;-.4,-3.85,;-1.73,-3.08,;-1.73,-1.54,;-.4,-.77,;.94,-1.54,;-3.06,-.77,;-3.06,.77,;-4.53,1.25,;-5.43,0,;-6.96,-.16,;-7.59,-1.56,;-6.69,-2.81,;-5.15,-2.65,;-4.53,-1.24,)| Show InChI InChI=1S/C21H21N5O/c22-15-8-10-16(11-9-15)27-18-5-3-4-14-7-12-17(23-20(14)18)21-25-24-19-6-1-2-13-26(19)21/h1-7,12-13,15-16H,8-11,22H2/t15-,16?	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.75	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair