BDBM104196 US8575145, 73

SMILES: COC1(COc2cccc3ccc(nc23)-c2nnc3ccccn23)CCNCC1

InChI Key: InChIKey=NNCWGHBKJIEMSS-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 104196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM104196 (US8575145, 73) Show SMILES COC1(COc2cccc3ccc(nc23)-c2nnc3ccccn23)CCNCC1 Show InChI InChI=1S/C22H23N5O2/c1-28-22(10-12-23-13-11-22)15-29-18-6-4-5-16-8-9-17(24-20(16)18)21-26-25-19-7-2-3-14-27(19)21/h2-9,14,23H,10-13,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.960	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PIM-3 (Rattus norvegicus (Rat))	BDBM104196 (US8575145, 73) Show SMILES COC1(COc2cccc3ccc(nc23)-c2nnc3ccccn23)CCNCC1 Show InChI InChI=1S/C22H23N5O2/c1-28-22(10-12-23-13-11-22)15-29-18-6-4-5-16-8-9-17(24-20(16)18)21-26-25-19-7-2-3-14-27(19)21/h2-9,14,23H,10-13,15H2,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM104196 (US8575145, 73) Show SMILES COC1(COc2cccc3ccc(nc23)-c2nnc3ccccn23)CCNCC1 Show InChI InChI=1S/C22H23N5O2/c1-28-22(10-12-23-13-11-22)15-29-18-6-4-5-16-8-9-17(24-20(16)18)21-26-25-19-7-2-3-14-27(19)21/h2-9,14,23H,10-13,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	79	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair