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SMILES: Nc1ncc(cn1)-c1ccc(cn1)C1(CCC1)c1noc(n1)-c1ccc(nc1)N1CCC[C@@H]1CO

InChI Key: InChIKey=ZAHJRHXBXUDDMG-LJQANCHMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104554   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Arachidonate 5-lipoxygenase-activating protein


(Homo sapiens (Human))		BDBM104554
PNG
(US8575201, 45)
Show SMILES Nc1ncc(cn1)-c1ccc(cn1)C1(CCC1)c1noc(n1)-c1ccc(nc1)N1CCC[C@@H]1CO |r|
Show InChI InChI=1S/C25H26N8O2/c26-24-29-12-17(13-30-24)20-6-5-18(14-27-20)25(8-2-9-25)23-31-22(35-32-23)16-4-7-21(28-11-16)33-10-1-3-19(33)15-34/h4-7,11-14,19,34H,1-3,8-10,15H2,(H2,26,29,30)/t19-/m1/s1
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Similars
US Patent
n/an/a 3.10n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds area assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP i...

US Patent US8575201 (2013)


BindingDB Entry DOI: 10.7270/Q2ZK5FBX
More data for this
Ligand-Target Pair