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SMILES: C[C@H](O)CNc1ccc(cn1)-c1nc(no1)C1(CCC1)c1ccc(nc1)-c1cnc(N)nc1

InChI Key: InChIKey=WPHQQXMDMLEWSV-AWEZNQCLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104555   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Arachidonate 5-lipoxygenase-activating protein


(Homo sapiens (Human))		BDBM104555
PNG
(US8575201, 46)
Show SMILES C[C@H](O)CNc1ccc(cn1)-c1nc(no1)C1(CCC1)c1ccc(nc1)-c1cnc(N)nc1 |r|
Show InChI InChI=1S/C23H24N8O2/c1-14(32)9-26-19-6-3-15(10-27-19)20-30-21(31-33-20)23(7-2-8-23)17-4-5-18(25-13-17)16-11-28-22(24)29-12-16/h3-6,10-14,32H,2,7-9H2,1H3,(H,26,27)(H2,24,28,29)/t14-/m0/s1
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Similars
US Patent
n/an/a 2.40n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds area assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP i...

US Patent US8575201 (2013)


BindingDB Entry DOI: 10.7270/Q2ZK5FBX
More data for this
Ligand-Target Pair