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SMILES: CN1CCN(CC1)c1cnc(cn1)-c1nc(no1)C1(CCC1)c1ccc(nc1)-c1cnc(N)nc1

InChI Key: InChIKey=YZWITWIIFHPURC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104570   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Arachidonate 5-lipoxygenase-activating protein


(Homo sapiens (Human))		BDBM104570
PNG
(US8575201, 61)
Show SMILES CN1CCN(CC1)c1cnc(cn1)-c1nc(no1)C1(CCC1)c1ccc(nc1)-c1cnc(N)nc1
Show InChI InChI=1S/C24H26N10O/c1-33-7-9-34(10-8-33)20-15-27-19(14-28-20)21-31-22(32-35-21)24(5-2-6-24)17-3-4-18(26-13-17)16-11-29-23(25)30-12-16/h3-4,11-15H,2,5-10H2,1H3,(H2,25,29,30)
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Similars
US Patent
n/an/a 1.80n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds area assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP i...

US Patent US8575201 (2013)


BindingDB Entry DOI: 10.7270/Q2ZK5FBX
More data for this
Ligand-Target Pair