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SMILES: Nc1ncc(cn1)-c1ccc(cn1)C1(CCC1)c1noc(n1)-c1ccc2[nH]ncc2c1

InChI Key: InChIKey=RZMMYWOGWXTTOQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104588   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Arachidonate 5-lipoxygenase-activating protein


(Homo sapiens (Human))		BDBM104588
PNG
(US8575201, 79)
Show SMILES Nc1ncc(cn1)-c1ccc(cn1)C1(CCC1)c1noc(n1)-c1ccc2[nH]ncc2c1
Show InChI InChI=1S/C22H18N8O/c23-21-25-9-15(10-26-21)17-5-3-16(12-24-17)22(6-1-7-22)20-28-19(31-30-20)13-2-4-18-14(8-13)11-27-29-18/h2-5,8-12H,1,6-7H2,(H,27,29)(H2,23,25,26)
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Similars
US Patent
n/an/a 4n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds area assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP i...

US Patent US8575201 (2013)


BindingDB Entry DOI: 10.7270/Q2ZK5FBX
More data for this
Ligand-Target Pair