BDBM104707 US8569311, 1-34
SMILES: C[C@@H]1CC[C@@H](COc2ccc(F)cn2)CN1C(=O)c1c(F)cccc1-c1ncccn1
InChI Key: InChIKey=OYFDBWSFFPTFSO-HZPDHXFCSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Orexin receptor type 2 (OX2) (Rattus norvegicus (Rat)) | BDBM104707 (US8569311, 1-34) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merch Sharp & Dohme Corp. US Patent | Assay Description Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430. | US Patent US8569311 (2013) BindingDB Entry DOI: 10.7270/Q2TT4PM6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 1 (OX1) (Rattus norvegicus (Rat)) | BDBM104707 (US8569311, 1-34) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merch Sharp & Dohme Corp. US Patent | Assay Description Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430. | US Patent US8569311 (2013) BindingDB Entry DOI: 10.7270/Q2TT4PM6 | |||||||||||
More data for this Ligand-Target Pair |