BDBM104819 US8569299, 8
SMILES: CN(C)[C@]1(C)C[C@H]([C@@H](C1)c1ccc(F)cc1F)C(=O)N1CCC(CC1)c1cc(C)nn1-c1ccc(Cl)c(Cl)c1
InChI Key: InChIKey=XMOICBGWKUUJPT-BBANNHEPSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human)) | BDBM104819 (US8569299, 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo... | US Patent US8569299 (2013) BindingDB Entry DOI: 10.7270/Q2K9365V | |||||||||||
More data for this Ligand-Target Pair |