BDBM105198 5‐bromo‐3‐hydroxy‐1,2‐dihydropyridin‐2‐one (Compound 2)

SMILES: Oc1cc(Br)c[nH]c1=O

InChI Key: InChIKey=KXBXUHWCODHRHK-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
H1N1 Endonuclease (2009 H1N1 Influenza)	BDBM105198 (5‐bromo‐3‐hydroxy‐1,2̴...) Show SMILES Oc1cc(Br)c[nH]c1=O Show InChI InChI=1S/C5H4BrNO2/c6-3-1-4(8)5(9)7-2-3/h1-2,8H,(H,7,9)	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rutgers University					Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...				ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW
					More data for this Ligand-Target Pair				3D Structure (crystal)