BDBM106150 US9695172, 3
SMILES: COc1cc(ccc1Nc1ccc2N(C)C(=O)c3ccccc3N(C)c2n1)C(=O)N1CCC(CC1)N1CCN(C)CC1
InChI Key: InChIKey=SZURENOYVUBGEB-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM106150 (US9695172, 3) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.37E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Dana-Farber Cancer Institute, Inc. US Patent | Assay Description Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ... | US Patent US9695172 (2017) BindingDB Entry DOI: 10.7270/Q2JD4TX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human)) | BDBM106150 (US9695172, 3) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Dana-Farber Cancer Institute, Inc. US Patent | Assay Description Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ... | US Patent US9695172 (2017) BindingDB Entry DOI: 10.7270/Q2JD4TX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain testis-specific protein (Homo sapiens (Human)) | BDBM106150 (US9695172, 3) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.68E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Dana-Farber Cancer Institute, Inc. US Patent | Assay Description Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ... | US Patent US9695172 (2017) BindingDB Entry DOI: 10.7270/Q2JD4TX8 | |||||||||||
More data for this Ligand-Target Pair |