BDBM10657 US8846719, 280

SMILES: CCNC(=O)c1ccc(OCc2c(C)onc2C2CCCCN2)nc1

InChI Key: InChIKey=JZXTWCYSLIVPCZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A)) (Homo sapiens (Human))	BDBM10657 (US8846719, 280) Show SMILES CCNC(=O)c1ccc(OCc2c(C)onc2C2CCCCN2)nc1 Show InChI InChI=1S/C18H24N4O3/c1-3-19-18(23)13-7-8-16(21-10-13)24-11-14-12(2)25-22-17(14)15-6-4-5-9-20-15/h7-8,10,15,20H,3-6,9,11H2,1-2H3,(H,19,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	-11.4	n/a	n/a	n/a	n/a	n/a	7.5	4
Roche Palo Alto LLC US Patent					Assay Description Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...				US Patent US8846719 (2014) BindingDB Entry DOI: 10.7270/Q2V986RV
					More data for this Ligand-Target Pair