BDBM10668 US8846719, 285

SMILES: COCCNC(=O)c1ccc(OCc2c(C)onc2C2CCCCN2)nc1

InChI Key: InChIKey=RMGRVWWGRIGWRJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10668   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A)) (Homo sapiens (Human))	BDBM10668 (US8846719, 285) Show SMILES COCCNC(=O)c1ccc(OCc2c(C)onc2C2CCCCN2)nc1 Show InChI InChI=1S/C19H26N4O4/c1-13-15(18(23-27-13)16-5-3-4-8-20-16)12-26-17-7-6-14(11-22-17)19(24)21-9-10-25-2/h6-7,11,16,20H,3-5,8-10,12H2,1-2H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	-11.4	n/a	n/a	n/a	n/a	n/a	7.5	4
Roche Palo Alto LLC US Patent					Assay Description Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...				US Patent US8846719 (2014) BindingDB Entry DOI: 10.7270/Q2V986RV
					More data for this Ligand-Target Pair