BDBM107107 US8592425, 92

SMILES: N[C@H]1CCCC(F)(F)C1NC(=O)c1nc(c(Cl)s1)-c1cnc2ccccn12

InChI Key: InChIKey=NZQSJPMVPFYPKC-LLTODGECSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase c-TAK1 (Homo sapiens (Human))	BDBM107107 (US8592425, 92) Show SMILES N[C@H]1CCCC(F)(F)C1NC(=O)c1nc(c(Cl)s1)-c1cnc2ccccn12 |r| Show InChI InChI=1S/C17H16ClF2N5OS/c18-14-12(10-8-22-11-5-1-2-7-25(10)11)23-16(27-14)15(26)24-13-9(21)4-3-6-17(13,19)20/h1-2,5,7-9,13H,3-4,6,21H2,(H,24,26)/t9-,13?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description MARK3 activity was assayed in vitro using a Cdc25C biotinylated peptide substrate (Cell Signalling Technologies). The phosphopeptide product was quan...				US Patent US8592425 (2013) BindingDB Entry DOI: 10.7270/Q28P5Z48
					More data for this Ligand-Target Pair