BDBM107108 US8592425, 1

SMILES: Cc1sc(cc1-c1cnc2cccnn12)C(=O)NC1[C@H](N)CCCC1(F)F

InChI Key: InChIKey=RBKSVWDPSJPWNC-ZGTOLYCTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase c-TAK1 (Homo sapiens (Human))	BDBM107108 (US8592425, 1) Show SMILES Cc1sc(cc1-c1cnc2cccnn12)C(=O)NC1[C@H](N)CCCC1(F)F |r| Show InChI InChI=1S/C18H19F2N5OS/c1-10-11(13-9-22-15-5-3-7-23-25(13)15)8-14(27-10)17(26)24-16-12(21)4-2-6-18(16,19)20/h3,5,7-9,12,16H,2,4,6,21H2,1H3,(H,24,26)/t12-,16?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description MARK3 activity was assayed in vitro using a Cdc25C biotinylated peptide substrate (Cell Signalling Technologies). The phosphopeptide product was quan...				US Patent US8592425 (2013) BindingDB Entry DOI: 10.7270/Q28P5Z48
					More data for this Ligand-Target Pair