BDBM107111 US8592425, 24

SMILES: CCc1sc(cc1-c1cnc2cc(C)cnn12)C(=O)NC1[C@H](N)CCCC1(F)F

InChI Key: InChIKey=WGNQNMPDQIMYJJ-YJJYDOSJSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP/microtubule affinity-regulating kinase 3 (Homo sapiens (Human))	BDBM107111 (US8592425, 24) Show SMILES CCc1sc(cc1-c1cnc2cc(C)cnn12)C(=O)NC1[C@H](N)CCCC1(F)F |r| Show InChI InChI=1S/C20H23F2N5OS/c1-3-15-12(14-10-24-17-7-11(2)9-25-27(14)17)8-16(29-15)19(28)26-18-13(23)5-4-6-20(18,21)22/h7-10,13,18H,3-6,23H2,1-2H3,(H,26,28)/t13-,18?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description MARK3 activity was assayed in vitro using a Cdc25C biotinylated peptide substrate (Cell Signalling Technologies). The phosphopeptide product was quan...				US Patent US8592425 (2013) BindingDB Entry DOI: 10.7270/Q28P5Z48
					More data for this Ligand-Target Pair