BDBM107159 US8592426, 8

SMILES: Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(COC1)NC(=O)C(F)(F)F

InChI Key: InChIKey=YOFLVURHBHANJB-KRWDZBQOSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin-1 Receptor (Homo sapiens (Human))	BDBM107159 (US8592426, 8) Show SMILES Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(COC1)NC(=O)C(F)(F)F |r| Show InChI InChI=1S/C23H19ClF4N6O3/c1-34-32-19(31-33-34)18-15(7-13(24)8-16(18)25)12-2-4-14-11(6-12)3-5-17(14)29-20(35)22(9-37-10-22)30-21(36)23(26,27)28/h2,4,6-8,17H,3,5,9-10H2,1H3,(H,29,35)(H,30,36)/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	30.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Binding assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair
Bradykinin-1 Receptor (Homo sapiens (Human))	BDBM107159 (US8592426, 8) Show SMILES Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(COC1)NC(=O)C(F)(F)F |r| Show InChI InChI=1S/C23H19ClF4N6O3/c1-34-32-19(31-33-34)18-15(7-13(24)8-16(18)25)12-2-4-14-11(6-12)3-5-17(14)29-20(35)22(9-37-10-22)30-21(36)23(26,27)28/h2,4,6-8,17H,3,5,9-10H2,1H3,(H,29,35)(H,30,36)/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24.4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Calcium mobilization assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair