BDBM107162 US8592426, 11

SMILES: Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2C(CCCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F

InChI Key: InChIKey=IAWVOODBIZSXKE-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin-1 Receptor (Homo sapiens (Human))	BDBM107162 (US8592426, 11) Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2C(CCCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F Show InChI InChI=1S/C25H21ClF4N4O3/c1-12-31-21(34-37-12)20-17(10-15(26)11-18(20)27)14-5-6-16-13(9-14)3-2-4-19(16)32-22(35)24(7-8-24)33-23(36)25(28,29)30/h5-6,9-11,19H,2-4,7-8H2,1H3,(H,32,35)(H,33,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	41.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Binding assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair
Bradykinin-1 Receptor (Homo sapiens (Human))	BDBM107162 (US8592426, 11) Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2C(CCCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F Show InChI InChI=1S/C25H21ClF4N4O3/c1-12-31-21(34-37-12)20-17(10-15(26)11-18(20)27)14-5-6-16-13(9-14)3-2-4-19(16)32-22(35)24(7-8-24)33-23(36)25(28,29)30/h5-6,9-11,19H,2-4,7-8H2,1H3,(H,32,35)(H,33,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Calcium mobilization assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair