BDBM107167 US8592426, 16

SMILES: Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1cc2CCC(NC(=O)C3(CC3)NC(=O)C(F)(F)F)c2c(F)c1

InChI Key: InChIKey=RLZPVLDPNQNXFY-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kininogen-1 (Homo sapiens (Human))	BDBM107167 (US8592426, 16) Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1cc2CCC(NC(=O)C3(CC3)NC(=O)C(F)(F)F)c2c(F)c1 Show InChI InChI=1S/C24H18ClF5N4O3/c1-10-31-20(34-37-10)19-14(8-13(25)9-16(19)27)12-6-11-2-3-17(18(11)15(26)7-12)32-21(35)23(4-5-23)33-22(36)24(28,29)30/h6-9,17H,2-5H2,1H3,(H,32,35)(H,33,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Binding assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair
Kininogen-1 (Homo sapiens (Human))	BDBM107167 (US8592426, 16) Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1cc2CCC(NC(=O)C3(CC3)NC(=O)C(F)(F)F)c2c(F)c1 Show InChI InChI=1S/C24H18ClF5N4O3/c1-10-31-20(34-37-10)19-14(8-13(25)9-16(19)27)12-6-11-2-3-17(18(11)15(26)7-12)32-21(35)23(4-5-23)33-22(36)24(28,29)30/h6-9,17H,2-5H2,1H3,(H,32,35)(H,33,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Calcium mobilization assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair