BDBM107196 US8592426, 46

SMILES: Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2C(COc2c1)NC(=O)C1(CC1)NC(=O)c1ccnnc1

InChI Key: InChIKey=UFPMXLUTBQTILN-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kininogen-1 (Homo sapiens (Human))	BDBM107196 (US8592426, 46) Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2C(COc2c1)NC(=O)C1(CC1)NC(=O)c1ccnnc1 Show InChI InChI=1S/C26H20ClFN6O4/c1-13-31-23(34-38-13)22-18(9-16(27)10-19(22)28)14-2-3-17-20(12-37-21(17)8-14)32-25(36)26(5-6-26)33-24(35)15-4-7-29-30-11-15/h2-4,7-11,20H,5-6,12H2,1H3,(H,32,36)(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	19.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Binding assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair
Kininogen-1 (Homo sapiens (Human))	BDBM107196 (US8592426, 46) Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2C(COc2c1)NC(=O)C1(CC1)NC(=O)c1ccnnc1 Show InChI InChI=1S/C26H20ClFN6O4/c1-13-31-23(34-38-13)22-18(9-16(27)10-19(22)28)14-2-3-17-20(12-37-21(17)8-14)32-25(36)26(5-6-26)33-24(35)15-4-7-29-30-11-15/h2-4,7-11,20H,5-6,12H2,1H3,(H,32,36)(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Calcium mobilization assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair