BDBM10732 3-amino-2,3-dihydro-1H-inden-5-yl N-(4-methoxyphenyl)-N-methylcarbamate::Aminoindan deriv. 7f

SMILES: COc1ccc(cc1)N(C)C(=O)Oc1ccc2CCC(N)c2c1

InChI Key: InChIKey=KLKHEERGMBJKHN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Butyrylcholinesterase (BChE) (Equus caballus (Horse))	BDBM10732 (3-amino-2,3-dihydro-1H-inden-5-yl N-(4-methoxyphen...) Show SMILES COc1ccc(cc1)N(C)C(=O)Oc1ccc2CCC(N)c2c1 Show InChI InChI=1S/C18H20N2O3/c1-20(13-5-8-14(22-2)9-6-13)18(21)23-15-7-3-12-4-10-17(19)16(12)11-15/h3,5-9,11,17H,4,10,19H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Teva Pharmaceutical Industries					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...				J Med Chem 45: 5260-79 (2002) Article DOI: 10.1021/jm020120c BindingDB Entry DOI: 10.7270/Q2GQ6W07
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM10732 (3-amino-2,3-dihydro-1H-inden-5-yl N-(4-methoxyphen...) Show SMILES COc1ccc(cc1)N(C)C(=O)Oc1ccc2CCC(N)c2c1 Show InChI InChI=1S/C18H20N2O3/c1-20(13-5-8-14(22-2)9-6-13)18(21)23-15-7-3-12-4-10-17(19)16(12)11-15/h3,5-9,11,17H,4,10,19H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	37
Teva Pharmaceutical Industries					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...				J Med Chem 45: 5260-79 (2002) Article DOI: 10.1021/jm020120c BindingDB Entry DOI: 10.7270/Q2GQ6W07
					More data for this Ligand-Target Pair